WebApr 1, 2024 · Serafini-Cessi F, Malagolini N, Cavallone D. Tamm-Horsfall glycoprotein: biology and clinical relevance. Am J Kidney Dis. 2003;42:658–676. doi: 10.1016/S0272-6386(03)00829-1. Fukuoka S, Kobayashi K. Analysis of the C-terminal structure of urinary Tamm-Horsfall protein reveals that the release of the glycosyl phosphatidylinositol … Web178 Tamm-Horsfall urinary glycoprotein antibodies from 24 antibody suppliers Click each Tamm-Horsfall urinary glycoprotein antibody that interests you to view the full Tamm-Horsfall urinary glycoprotein antibody datasheet. View only Tamm-Horsfall urinary glycoprotein Monoclonal Antibodies or Tamm-Horsfall urinary glycoprotein Polyclonal …
Tamm-Horsfall Protein - an overview ScienceDirect Topics
WebJan 1, 1999 · The N-glycosylation sites of human Tamm-Horsfall glycoprotein from one healthy male donor have been characterized, based on an approach using endoproteinase Glu-C (V-8 protease, Staphylococcus aureus ) digestion and a combination of chromatographic techniques, automated Edman sequencing, and fast atom … WebJan 14, 2024 · Tamm–Horsfall protein (THP) or uromodulin (gene name UMOD) is a 90-kDa protein produced almost exclusively in the kidney by the epithelial cells lining the thick ascending limb (TAL) of the loop of Henle and early distal tubules [ 1–3 ]. property tax living basement attic garage
Uromodulin (Tamm–Horsfall protein): guardian of urinary and …
Uromodulin (UMOD), also known as Tamm–Horsfall protein (THP), is a Zona pellucida-like domain-containing glycoprotein that in humans is encoded by the UMOD gene. Uromodulin is the most abundant protein excreted in ordinary urine. See more The human UMOD gene is located on chromosome 16. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of … See more THP is a GPI-anchored glycoprotein. It is not derived from blood plasma but is produced by the thick ascending limb of the loop of Henle of the mammalian kidney. While the … See more Uromodulin excretion in urine follows proteolytic cleavage of the ectodomain of its glycophosphatidylinositol-anchored counterpart that is … See more The glycoprotein was first purified in 1952 by Igor Tamm and Frank Horsfall from the urine of healthy individuals. It was later detected in the urine of all mammals studied. See more Uromodulin consists of an EGF domain (EGF I); two calcium-binding EGF domains (EGF II, III); a cysteine-rich decoy module consisting of a β-hairpin and a D10C domain (previously … See more Uropontin, nephrocalcin and uromodulin (this protein) are the three known urinary glycoproteins that affect the formation of calcium-containing See more • Scolari F, Viola BF, Ghiggeri GM, Caridi G, Amoroso A, Rampoldi L, Casari G (2003). "Towards the identification of (a) gene(s) for autosomal dominant medullary cystic kidney disease". Journal of Nephrology. 16 (3): 321–8. PMID 12832729. • Rindler MJ, Naik SS, Li N, Hoops … See more WebJul 20, 2024 · Tamm-Horsfall protein (THP) is a high molecular weight glycoprotein discovered by Tamm and Horsfall ( J Exp Med 1952;95:71 ) Normally synthesized by thick … WebIN 1950, IGOR TAMM and Frank Horsfall1 used a salt-precipitation procedure to isolate a potent inhibitor of viral hemoagglutination from urine of healthy individuals. Subsequently, … property tax loan texas