WebMar 11, 2024 · The TF GATA-3 is well-known for its function as a master regulator of Th2 responses ( 17 ). However, this TF is also involved in T-cell lineage commitment ( 18 ), having a pivotal role already during the transition of thymus-seeding progenitor cells into early T-lineage progenitors ( 19 ). WebOct 23, 2013 · In T-bet/GATA3>1 group, only 1 rejection episode had positive response …
Kidney GATA3+ regulatory T cells play roles in the ... - Nature
WebOct 3, 2011 · GATA3 expression in both murine and human Tregs was induced upon TCR and IL-2 stimulation. Although GATA3 was not required to sustain Treg homeostasis and function at steady state, GATA3 played a cardinal … WebDec 11, 2012 · T-bet and GATA3 regulate the CD4+ T cell Th1/Th2 cell fate decision but … talbot county ag center
Frontiers Revisiting the Concept of Targeting NFAT …
WebThere were no significant differences in the expressions of T-bet, GATA3, IFN-γ and IL-4 … WebRT @LabWaggoner: Silencer CNS–28 diminishes enhancer-promoter interactions within Ifng locus in a GATA3-dependent but T-bet-independent manner to ensure immune cell quiescence and minimize autoimmunity @ImmunityCP. 10 Apr 2024 16:18:57 WebTogether with IL-2-mediated STAT5 activation, TGF-β induces Treg differentiation; on the other hand, together with IL-6-mediated STAT3 activation, TGF-β induces Th17-cell differentiation (Bettelli et al. 2006; Veldhoen et al. 2006). IL-21 and IL-23 have a similar function as IL-6 in inducing STAT3 activation and, thus, Th17-cell differentiation. twitter john shipley