Web6 dec. 2024 · CAMBRIDGE, Mass. and CARLSBAD, Calif., Dec. 06, 2024 (GLOBE NEWSWIRE) -- Biogen Inc (Nasdaq: BIIB) and Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that Biogen exercised its option to obtain from Ionis a worldwide, exclusive, royalty-bearing license to develop and commercialize BIIB067 (IONIS-SOD1 … WebJuly 13, 2024 deal between Ionis and Bicycle for TfR1 tissue-targeted oligonucleotide delivery technology Jan. 25, 2024 study Antisense oligonucleotides as a potential treatment for brain deficits observed in myotonic dystrophy type 1
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Web14 jul. 2024 · 根据许可和合作协议的条款,Ionis 和 Bicycle 将合作开发一系列使用组织靶向 TfR1 Bicycle 技术交付的寡核苷酸治疗产品候选产品 ,而 Bicycle 保留将 TfR1 Bicycles 用于所有非寡核苷酸治疗目的的权利,包括与 DDF 针对痴呆症的现有合作。 2024-07-14 16:46 雪球 转发:0 回复:0 喜欢:0 Web20 jul. 2024 · Ionis Pharmaceuticals is paying $45 million upfront for the exclusive right to binders for the delivery of oligonucleotides to tissues expressing TfR1. The deal leaves … granting full freedom in 1838
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Web. Ionis' new generation of ligand-coupled antisense technology allows ASO drugs to be administered in a variety of ways and delivered to various organs and tissues of the … Web18 jul. 2024 · Ionis此前已在偶联分子药物的项目上积累了一定的成果。例如,将GalNAc和GLP-1肽等分子与反义寡核苷酸结合,可使其更多的药物化合物靶向包括肝细胞和胰腺中的β细胞在内的靶点。此次与Bicycle的合作旨在使用Bicycle公司的合成双环肽技术来改善这个 … Web20 feb. 2024 · The drug, IONIS-AZ5-2.5RX, or AZD2373, will inhibit an undisclosed target, and AZ will be responsible for development and marketing. Ionis will receive $30 million upfront and may also receive up ... granting hope society