WebAnti-BCMA surface engineered biomimetic photothermal nanomissile enhances multiple myeloma cell apoptosis and overcomes the disturbance of NF-κB signaling in vivo. Xiaojuan Xiao, Zekang Ma, Zhenzhen Li, Yiyi Deng, ... Jing Liu. In Press, Journal Pre-proof, Available online 17 March 2024. WebFeb 13, 2024 · Overall, vancomycin-loaded PMMA and PG-CSH beads showed potency (ZOI above 4 cm 2) for up to 14 days against ATCC and clinical strains. Vancomycin ... PMMA has been regarded as the gold standard in the prophylaxis and treatment of bone infections ... we compared the in vitro vancomycin elution characteristics of two bone …
Biomaterials approaches to treating implant-associated osteomyelitis
WebOct 1, 2024 · Therefore, the biofilm increases the pathogenesis of infection since that structure offers protection against host defenses and antimicrobial therapies. Additionally, the rapid emergence of bacterial strains resistant to antibiotics prompted the development of new alternative approaches to prevent and control implant-related infections. WebSep 15, 2024 · Bone infection. Biomaterial-assisted delivery of bacteriophages has ... M. et al. MRGPR-mediated activation of local mast cells clears cutaneous bacterial … chinmaya somnath summer camp
Scaffold-based Anti-infection Strategies in Bone Repair
WebDec 5, 2014 · Bone fractures and non-union defects often require surgical intervention where biomaterials are used to correct the defect, and approximately 10% of these procedures are compromised by bacterial infection. Currently, treatment options are limited to sustained, high doses of antibiotics and surgical debridement of affected tissue, … WebOct 22, 2024 · They highlight scaffolds that closely mimic natural bone tissue and immunomodulatory biomaterials that can prevent infection and promote cell survival for guiding and enhancing bone regeneration. WebApr 21, 2024 · The overall goal of my infection research program is to increase efficacy against S. aureus osteomyelitis by designing delivery vehicles that are better equipped at localizing therapeutics for prolonged bioavailability at the site of infection. Recently, we have begun leveraging chitosan-based biomaterials, which possess inherent … chinmaya schools in kerala